So, you wanna make homemade liposomal vitamin C ?

On the Internet, especially on YouTube, you can read and see how to make liposomal vitamin C by yourself. Here, we show and explain that and why it is impossible to make such a product yourself.

Making liposomal vitamin C yourself: please read this page first

Making liposomal vitamin C at home is pretty much impossible for the layman, except you have the necessary knowledge and of course the expensive machines and accessories.

To produce a truly liposomal product, you need a nanotechnology process. So what does that mean?
Nano stands for nanometer (nm). A nanometer is the millionth part of a millimeter = 0.000 001 mm, or 1 million times smaller than a millimeter. The scale relevant to us is 1-100 nm. Objects of these sizes cannot be seen by eye or with an optical microscope; you would need an electron microscope.
So, you can only call something a nanoproduct if it has a main fraction of 1-150 nm, which according to our quality guarantee, as you can see, is really true for our products.

homemade-selfmade liposomal vitamin c

Size scale comparison

  • 1 meter 
  • centimeter
  • millimeter
  • micrometer (Bacteria usually measure 10-50 µm (micrometers) but can be up to 700 µm in size).
  • nanometer (Viruses measure around 50 nm but can be up to 400 nm).
  • picometer (one billion picometers equal 1 millimeter)

Why does a liposomal drink have to have such small particles?

This is the most crucial point: a vitamin C liposome, in order to achieve the best bioavailability, must be about 100-250 nm in size. This size is relevant for absorption through the intestine, passage into the bloodstream, and onward transport to our cells where it is needed.
To support our own explanation, here are two derived from numerous scientific studies (in English).
The size scale of liposomes varies, but a mean size near 100 nm is quite typical.
…and, from 2018…
Particles in the size of below 200 nm for targeting tumour tissues.
If these particles are larger than 250 nm, they cannot be optimally absorbed by the intestinal villi and are excreted through the intestines, significantly lowering their bioavailability.
Some readers may now realize what the terms bioavailability and particle size are all about, and how important it is to purchase a genuine nanoproduct. Only a liposome of the required smallness in the nanoscale mentioned above can dock onto the cell to deliver its contents to it. Only a nanoproduct thus offers the health benefits of the liposomal form in addition to the convenient intake.

You Tube ultra sonic cleaner

Let’s take a brief look at the internet / YouTube demos where so-called ultrasonic cleaners are used to produce liposomal vitamin C at home. It is indeed possible to reduce particles with ultrasound. However, no ultrasonic cleaner can achieve that, no matter how strong. A cleaner is just not made for this purpose because it is supposed to clean glasses, jewelry, cutlery, tools and so on, not to crush particles. It is, as the name suggests, an ultrasonic cleaner.

The metal vessel of such an ultrasonic cleaner would be shredded and dissolve into its components at the enormous energy that it takes to create nanoparticles!
In addition, ultrasonic cleaners operate at a frequency of mostly 40-50 KHz, which is useless for liposomal production. For this purpose, 20 KHz are required.


Particle size of a Liposome

Of course, everyone is free to doubt our statements and explanations. You can only be sure if you subject your self-produced ‘liposomal’ beverage to a particle measurement. This is done, for example, by the company in Germany where we have our products periodically checked. These particle measurements using laser technology in turn require special and expensive equipment and the associated expertise, which we lack. If you produce liposomal(?) vitamin C yourself and do not want to lie to yourself and are critical, then the above address is exactly right for you.


Producing liposomal vitamin C yourself requires the necessary machinery, laboratory equipment and expertise, in addition to the financial investment, of course, which is not really small, even if you use some common lab equipment and small quantities at home. So, you actually need special machines and materials that can withstand such vibrations and forces. A special generator produces these frequencies with a power of about 3000 watts, which is delivered to the liquid in a highly concentrated form by a so-called sonotrode with a diameter of just 3-4 cm.

These machines have a very complex design. Part of this enormous energy is converted into heat, which requires a suitable cooling system. Lecithin does not tolerate high heat because it is a lipid. Also needed are pumps, valves and special pressure vessels to achieve the right consistency and shelf life. Endless chrome steel lines and pressure regulators complete the equipment.

The sonotrode is the end piece of such an apparatus, and it fulfils the purpose of crushing the surrounding medium. It is the part that absorbs the high vibrational energy and delivers it to the medium (in our case, the “pre-liposomal” mixture.

liposomal production with this first step machine


This actual head of the ultrasonic system is made of high-grade titanium, because no other material can withstand these large focused energies. Still, these hard titanium sonotrodes very soon become perforated and need to be replaced frequently.

At the tip of this sonotrode, there are cavitation velocities of over 1000 km/h!  This may give you an idea of the enormous forces acting on the fluid! It should be clear now that producing genuine liposomal vitamin C is not quite as simple as the demos on YouTube would have you believe.

The operation of the sonotrode is accompanied by a very loud, penetrating high-frequency whistling sound. To work with such an apparatus at home would probably call the police as well as the fire department into action… Besides, a sonotrode with generator and transducer costs about EUR 19000, and can be obtained from the company Hielscher Ultrasonic in Germany.


This picture shows a new sonotrode made of titanium with a smooth surface.

sonotrode-head from titanium-used

And here is a used sonotrode in visibly perforated condition.

So what do do now?

Quite frankly, we want to give the private and prospective “liposome manufacturers” the bare facts. That is why we are not afraid to disclose the corresponding companies in our links.

Please do not be fooled by the videos and instructions on the Internet. Ultimately, when you have your “liposomal vitamin C” tested according to the instructions on the Internet, you will see that the whole financial effort (mixer, ultrasonic cleaner, lecithin and vitamin C) was not worth it, even if you would get these utensils as a gift. To sum up, it is not possible to produce real liposomal vitamin C on a nanobasis by yourself.

messy kitchen

What you get when following these internet instructions is a simple emulsion-like substance containing vitamin C, lecithin, and water, but never a liposomal product, and you could just as well take vitamin C tablets or capsules to meet your vitamin C needs, which would be much cheaper to boot, and without messing up your kitchen.